I have just finished porting the aqua version of LyX (which I need for @work), which is going to become aqua/lyx-mac. Version 1.5.x needs Qt4, which we do not have on MirOS just yet, and the Mac version installs into an application bundle, so it is a completely separate port.
First of all, I discovered TWO bugs in Qt's build system. Not only are the generated .la files wrong, but the .pc files are broken, too. My first bug report contained lots of detail but what finally landed in their bad joke of a bug tracking system is a one-liner. That should teach me not to write bug reports longer than one line ... Seriously, WTF?
Next, our pkg-config (both actually, pkgconfig-bsd is not better) does not grok frameworks. In order to get a correct result, I had to port pkg-config-0.23. It is not in the trunk yet because I was told that newer versions "make bad things happen" on MirOS. What I will do is try to build some stuff using this newer version of pkgconfig and try to find out if it works. So, if you are feeling lucky: Install this and try to build some software on MirOS.